SEARCH
Proteins
Reagents
Website
Home
About
Project
Admin Center
Proteomics Research Centers
Scientific Working Group
News & Events
News
Newsletter
Presentations
Meetings
Annual Programmatic
Community
Resources
Biodefense Proteomics Catalog
Master Protein Directory
Master Reagent Directory
Proteomics Data Center
NIAID Repositories
BEI
PFGRC
Other Repositories
PlasmID
FTP Download Site
Tools
Tutorials
Publications
Community Links
Site Map
Feedback
Select an Option
Data type
Organisms
Protein search
Summary
Technology Detail
Technology Description
The visual Platform for Proteomics Peptide and Protein data exploration (PQuad) is a multi-resolution environment that visually integrates genomic and proteomic data for prokaryotic systems, overlays categorical annotation and compares differential expression experiments.
Category
Software
PRC
Pacific Northwest National Laboratory
PubMed ID
17483503
Author
Bobbie Jo M. Webb Robertson, Elena S. Peterson, Mudita Singha, Kyle R. Klicker, Chris-topher S. Oehmen, Joshua N. Adkins and Susan L. Havre
Publication Description
PQuad offers the capability to map colors based on category definitions into the Genome and ORF Views. In the ORF View, for example, this would allow users to quickly identify if genes that are up-regulated in a microarray experiment are also expressed in the corresponding proteomic experiment. One of the most useful applications for categorical data integration is comparative proteomics to evaluate peptide/protein identification information from two or more different experimental conditions. Color is used to differentiate both peptide and protein expression across two experimental conditions.
Methodology
PQuad is a new visual analysis tool for proteomics that facilitates analysis of complex mixtures of proteins in multiple conditions for prokaryotic systems. Additionally, PQuad offers basic data integra-tion capabilities by mapping categorical information onto the pep-tide and protein expression data. Development as an object-oriented application allows new visualizations to be added rela-tively easily.
Resource
http://ncrr.pnl.gov/software/PQuad.stm