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Technology DescriptionVIPER: an advanced software package to support high-throughput LC-MS peptide identification
CategorySoftware
PRCPacific Northwest National Laboratory
PubMed ID17545182
AuthorMonroe ME, Tolic N, Jaitly N, Shaw JL, Adkins JN, Smith RD
Publication DescriptionThe Accurate Mass and Time (AMT) tag approach is used for analysis of large scale experiments by combining information generated over multiple datasets and instrument types.
MethodologyThe VIPER software package is one of the key components of the data processing pipeline and implements automated algorithms to discover LC-MS features, align and match these LC-MS features to a database of peptides previously identified in LC-MS/MS analyses, and identify and quantify pairs of isotopically labeled peptides.
Resourcehttp://ncrr.pnl.gov/software/VIPER.stm
Contact National Institute of Allergy and Infectious Disease National Institutes of Health National Institutes of Health