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Technology Description	MASIC (MS/MS Automated Selected Ion Chromatogram generator) generates selected ion chromatograms (SICs) for all of the parent ions chosen for fragmentation in an LC-MS/MS analysis.
Category	Technology
PRC	Pacific Northwest National Laboratory
Publication Description	The SICs are generated using the LC-MS data, then each SIC is processed using a peak finding algorithm to characterize the chromatographic peaks, providing peak statistics including elution time of the peak apex, peak area, and peak signal/noise. The program can read Finnigan .Raw files, mzXML files, mzData files or .cdf/.mgf combo files. Results are outputted both as flat files (.txt) and in an XML file that can be read using the accompanying graphical results browser.
Methodology	The browser provides a fast, graphical method for browsing the SICs identified by MASIC, allowing the user to sort and filter the SIC list as desired.
Resource	http://ncrr.pnl.gov/software/MASIC.stm