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Project NameMyriad protein to protein interaction through Y2H System
PRCMyriad Genetics
Project DescriptionIdentification of proteins involved in host/pathogen (Homo sapiens, B. anthracis, F. tularensis, Y. pestis, Vaccinia virus, Variola virus) interactions; Identification of biochemical pathways in pathogenic organisms; Identification of proteins binding to domains of membrane-associated proteins; Rapid translation of targets into high-throughput drug screens; Disrupting protein-protein interactions in high-throughput drug screens and elucidating protein-small molecule interactions; Elaboration of signaling and biochemical pathways and extension of biochemical pathways from previously uncharacterized genes.
Experiment DesignDirected yeast two-hybrid system sceening
Protein InteractionView
Experiment Data Downloads
FTP download
Request additional experiment data and details from max@myriad.com
Protocols
Protocol to Amplify an Activation Domain Library (Adl) >From the Permanent Frozen Stock
Reagent for Activation Domain Library Activation
ReagentsView
Visualization of predicted protein-protein interactionDisplay
Organisms
Homo sapiens, Mus musculus, Francisella tularensis
Contact National Institute of Allergy and Infectious Disease National Institutes of Health National Institutes of Health